Small building angles or toe-screw crossing boards?

[FDT]

A project where several 22 x 120 pieces will stand perpendicular to several 28 x 95 pieces. There will be many intersections...
How can I fasten them together in the smartest way?
Toe nailing is seen on TV shows, but I'm not familiar with it.

 

[Tjrex]

Are all the pieces loose?
If they are d, I would have laid them out and screwed from the back so d is hidden.

 

[FDT]

Are all the pieces loose?
If they are, I would lay them out and screw from the backside so it becomes hidden

Can access it from all sides. Will have to try to screw at an angle then

 

[prototypen]

Should the screw first go through 22, 120, 28, or 95 mm? Going through 22 mm is no issue, but if it needs to go through 120 mm, you'll require a screw about 150 mm long, which starts to get expensive.

Protte

 

[z_bumbi]

If accessible from all sides, screw from underneath.