With what you said in mind, I quite strongly advise against it. The hole-making doesn't seem absolutely necessary. 70x220 may be an impressive dimension, but with a 6 m span, you have no margins. When making large holes in beams, there are two areas you should avoid: Midway along the length and near the supports (the supports for the beams). The hole should be made at half the height of the beam. The problem with drainpipes is that they need to have a slope, and therefore the holes are often in the wrong height. A sink drain can be routed on the wall up to the vertical stack.