What is water-based paint? I once painted madonite with a water-soluble lacquer paint, it didn't go very well. It beaded up, but after a few layers, it sufficed for the application. Later, I painted a masonite with children's hobby paint, also water-soluble. It was a wall repair that I wanted to make a bit more discreet temporarily and it worked well. However, none of these paints are water-based.