What does the exterior wall look like? If it is plastered, there's a risk it will crack if you drill from the inside; in that case, I would rather sacrifice a tile. From what type of room are you drilling? Bathroom? Laundry room? etc.
I would use a hole saw for tiles and then drill further from there. If it's concrete hollow blocks or similar behind, you need to use percussion to get through, preferably a hammer drill when you have such dimensions.