In our house, we have similar spans but 45x220 c/c300 with bridging between the beams and then glued and screwed particle board on top, and it's completely solid - no signs of joint cracks in the tiles or ceramics at all. Our designer suggested that it would have worked with a larger cc measurement than 300 but not 600, plus it's from the outer wall to the load-bearing beam in the middle of the house, and on the other side of the beam, it's 600 mm between the beams, so we wanted it to be symmetrical with them. The solution was to add another 45x220 in between, so it became 300 cc. We have C24 and not C30.
I would think that it should work for you with 45x195, but it is good to place bridging between all the beams.